October 4, 2016

10516bipai640A program of Baylor College of Medicine International Pediatric AIDS Initiative (BIPAI), Texas Children’s Hospital and Chevron to improve health outcomes in a remote region of Colombia recently was awarded for its impact in the South American country.

Launched in January 2014, the initiative is based in La Guajira, one of the Colombia’s most impoverished states with a large indigenous community and high child and maternal mortality rates. Called SAIL (Salud y Autosuficiencia Indígenas en La Guajira), the program is a public-private partnership of Chevron, the central and departmental governments of Colombia, the state of La Guajira, and the Baylor College of Medicine Children’s Foundation-Colombia, an affiliate non-government organization of BIPAI. Currently, it is BIPAI’s only program in South America.

The SAIL program received a National Nutrition Award from the Exito Foundation, the charitable arm of Exito, Colombia’s largest retailer, in the category of Promoción Nutrición Materno Infantil – 1,000 days (advancing maternal-child nutrition in the first 1,000 days from conception). The award was presented at a ceremony September 7 in Bogota, Colombia.

“The early success of our program in Colombia is a reflection of BIPAI’s commitment to public-private partnership. We view ourselves as an extension of government’s public health programs. We aim to be complementary and never in conflict or competition with the good work others are doing.” said Dr. Mark W. Kline, chair and professor of pediatrics at Baylor College of Medicine and physician-in-chief at Texas Children’s Hospital.

“SAIL is a strategic initiative that enables comprehensive, locally driven health solutions for the Wayuu community. The program is being implemented in a very challenging environment, but we are witnessing impressive results,” said Ali Moshiri, president of Chevron Africa and Latin America Exploration and Production Company. “The National Nutrition Award is a recognition of this effort, but the real award is the potential and the opportunities for Wayuu mothers and children.”

“It’s a crowning achievement for our program to be honored in the area of nutrition, because very early on we recognized that in order to improve health in the region, we had to do something about the issue of malnutrition,” said Dr. James Thomas, professor of pediatrics at Baylor who leads the program for BIPAI. “There is a staggering amount of malnutrition in La Guajira.”

Forty percent of children have some form of malnutrition, Thomas said. It is one of the primary contributing factors to the high rate of mortality in children under age 5. Under 5 mortality and maternal mortality are two to four times higher in La Guajira than the national average, he said.

For the program to reach its goal of decreasing these high rates of child and maternal morbidity and mortality rates, Thomas and his colleagues knew they would have to take a different approach than the traditional Center of Excellence-based health care that has proven successful in BIPAI programs in sub-Saharan Africa. La Guajira is a desert region in northern Colombia, where its indigenous people, the Wayuu, live in remote settlements of open-air huts. They are a nomadic people, and their settlements are not easily accessible to one another or to the larger towns and cities in La Guajira where health care facilities are located.

A mobile health care platform was the best solution. Complemented initially by a BIPAI Global Health Corp pediatrician, a team of Guajirans was assembled, with the most critical members being nine indigenous women who were viewed as community leaders in their matrilineal society and had some healthcare experience. They received additional training focused on the integrated management of childhood illness. The team has expanded and now includes an OB-GYN and general practitioner. Leading the program on the ground in Colombia is executive director Dr. Ana Maria Galvis, who accepted the Exito award from First Lady of Colombia Maria Clemencia de Santos.

The team’s first step was to collect baseline data from the 172 Wayuu communities. This included weighing and measuring children, getting a basic health history and identifying at-risk patients.

In the first year of the program, more than 700 malnourished children were identified and treated by the interdisciplinary team who visited the rural settlements regularly. These efforts were boosted by a partnership with the Exito Foundation, which provides supplementary feeding for the indigenous Wayuu communities in the municipality of Manaure. At-risk families received a monthly food package, including items that are culturally accepted by the Wayuu community, until their malnourishment was reversed and they were no longer considered at risk. The Exito Foundation has placed an emphasis on eliminating malnutrition in Colombia by 2025.

Thomas emphasized the importance of providing treatment for malnutrition and other health care in the local community. “We knew that trying to provide treatment in health centers would not be effective,” he said. “It’s an incredible hardship on mothers and children to go to a clinic or hospital, in many cases requiring a four to five hour walk and leaving behind other children. Instead, we wanted to focus on identifying people in the early stages of disease in their own community.”

Other elements of the SAIL program include health fairs that have been conducted in numerous Wayuu communities and training sessions for health care workers in hospitals in the larger towns, where the main topic covered was identifying and treating malnutrition. The addition of an OB-GYN to the mobile health care team who provides check-ups during pregnancy has allowed the program to focus on the reduction of maternal mortality rates. Recent efforts in the area of maternal health have also focused on family planning. Wayuu women often have as many as eight or nine children, contributing to the issue of malnutrition, so family planning can have a direct impact on child health.

“When a mother dies not only is it an absolute tragedy for the family but is also an unsustainable loss for the community and country. The partnership in Colombia is a very real way to address maternal mortality and morbidity in the region, and addresses key aspects of obstetrics and prenatal care,” said Dr. Michael Belfort, chair and professor of obstetrics and gynecology at Baylor and obstetrician/gynecologist-in-chief at Texas Children’s Pavilion for Women. “We are already seeing tangible evidence of improved maternal care with our ultrasound and other educational programs that allow early diagnosis and treatment of problem pregnancies. It is a great pleasure to be able to help the remarkable team of Colombian physicians and nurses in this amazing project.”

Thomas acknowledged that addressing malnutrition has been a bigger piece of the health care puzzle in La Guajira than anticipated. By improving this health care concern, the focus can turn to other causes of disease.

More than 3,400 patients have already been directly seen through the program, and more than 300 health professionals have received training. Galvis expects its impact to continue since it was designed to be sustainable thanks to the involvement of the La Guajiran people. “It’s really their program, and this makes sense because it’s for their community,” she said.

Each success of the program is gratifying, Thomas said, but nothing is more gratifying than the opportunity to help the Wayuu people.

“There is a depth of personality in these people,” he said. “They are tapped into a traditional wisdom and belief system that has been there for centuries.”

July 19, 2016

72016jrreporters640A team of nurses, surgeons, and anesthesiologists from Texas Children’s Hospital’s Main Operating Room recently participated in a medical mission in Antigua, Guatemala.

The mission was coordinated by Faith in Practice, a Houston-based organization dedicated to the medical care of indigent people in Guatemala. The 44-member team that went consisted of medical and surgical staff from hospitals in the Medical Center and out of state. Among the volunteers from Texas Children’s were Drs. Olutoyin Olutoye, Oluyinka Olutoye, Robert Power, David Mann and Stephanie Cruz; certified registered nurse anesthetists Nate Jones and Megan Koudelka; and registered nurses Karen Bustos, Debra Batiste and Juan Sale.

Focusing primarily on pediatric patients, the team performed nearly 140 surgeries in just four days, including inguinal and umbilical hernias, orthopedic surgeries, podiatric cases, and dental extractions conducted in support of the people of Antigua.

“It is always a humbling experience to go on this mission trip,” said Bustos, who has been on the mission five times now. “These people come from villages eight to 10 hours away and come to us full of trust that we will make their children well.”

Sale, a first-time volunteer, said the trip was “an amazing experience, especially when you get to help the children.”

Glass, the group coordinator for Texas Children’s, said she has been participating in similar mission trips since 2002 and has gone to Guatemala 15 times.

“This activity is open to all surgeons, operating room nurses, anesthesia staff, recovery room nurses, and especially bilingual people,” Glass said, adding that financial donations will help support the mission as well as donation of unused OR supplies.

According to the organization’s website, Guatemala is considered extremely impoverished in comparison to other South American countries. Half of Guatemala’s 14 million people live in poverty, which is defined as living on less than $2 per day. In addition, the vast majority of Guatemalans have virtually no access to public health care.

In spite of these deficiencies, The Faith in Practice organization has made a significant impact on the people of Guatemala. In 2015 alone, 1,200 US volunteers travelled to Guatemala to participate in the mission activities coordinated by Faith in Practice. As a result, a total of 2,400 surgical procedures were performed and 25,000 Guatemalan patients were seen by the medical mission teams. Texas Children’s Hospital is extremely proud of this team and their selfless dedication to service.

June 21, 2016

62216globalhealth640Texas Children’s global health initiative recently expanded its services in Europe and Africa, enabling more children and adults across the globe to receive quality medical care. Two of the initiatives will help children in Africa who are suffering from cancer. The third effort will aid both adults and children living in Romania with HIV, hepatitis and tuberculosis.

Romania

The Romania initiative occurred June 6 when Baylor College of Medicine International Pediatric AIDS Initiative at Texas Children’s Hospital (BIPAI) formally opened the expansion of its center of excellence in Constanta, Romania, a port city hit hard by the AIDS epidemic.

“The addition of a third floor to our center of excellence marks an important milestone in our life-saving work here in Romania,” said Dr. Mark W. Kline, Texas Children’s Hospital physician-in-chief and BIPAI president. “What began as a center for children with HIV now has transitioned to a center for the long-term care of adults with HIV, along with the identification and care of patients with hepatitis and tuberculosis.”

AbbVie and the AbbVie Foundation (formerly Abbott and Abbott Fund) have been the lead sponsor of the BIPAI Romania program since its launch 15 years ago in 2001, investing $7.7 million in its HIV/AIDS and hepatitis programs, and providing $35.9 million in medications in partnership with AmeriCares.

“We are grateful for the opportunity to partner with BIPAI in Constanta for the past 15 years,” said Melissa Walsh, vice president of the AbbVie Foundation. “The program has become the model for many pediatric HIV/AIDS centers of excellence around the world, and we are proud to support the broadening of its life-saving work for patients, including liver disease.”

Malawi

The AbbVie Foundation, along with the Abbott Fund, also helped fund the recent cancer initiative in Malawi. On June 9, BIPAI, the AbbVie Foundation and the Malawi Ministry of Health reopened two renovated pediatric wards and dedicated a new pediatric hematology/oncology unit at Kamuzu Central Hospital.

“We are honored to celebrate this milestone for the Baylor College of Medicine and Texas Children’s Hospital,” Walsh said. “The Malawi program has transformed the lives of thousands of children and their families living with HIV/AIDS and we are so proud to support the expansion of that work into the pediatric cancer space.”

In addition to AbbVie, the Chevron Corporation also supports the Malawi program, funding its only pediatric oncologist, Dr. Peter Wasswa of Baylor College of Medicine and Texas Children’s Cancer Center.

“Today’s ceremony provides further evidence of our continued commitment to the children of Malawi,” said Michael Mizwa, chief operating officer, BIPAI, and director, Texas Children’s Global Health. “We look forward to another decade of expanding our programs to meet the needs of sick children, including care and treatment, professional education for physicians and other healthcare professionals, and ground-breaking research.”

Botswana

The second effort dedicated to helping children in Africa with cancer occurred on June 13 in Botswana when the Botswana-Baylor Children’s Center of Excellence and the government of Botswana signed a memorandum of agreement to build the first children’s hematology and cancer center of excellence in Gaborone.

“Approximately 40,000 children a year are diagnosed with cancer in sub-Saharan Africa and 20 percent of those children survive, compared with 80 percent in the U.S.,” said Dr. David Poplack, director of Texas Children’s Cancer and Hematology Centers. “This COE (Center of Excellence), in partnership with the Botswana Ministry of Health, will change those numbers in favor of the children of Botswana.”

When pediatric oncologists from Texas Children’s Hospital began working at Princess Marina Hospital in Gaborone, it was the first pediatric oncology program on the continent. The recent agreement between the Botswana-Baylor Children’s Center of Excellence and the government of Botswana expands that commitment to include the first stand-alone cancer center of excellence devoted exclusively to the treatment of children with cancer and blood diseases.

“The purpose of this agreement is to provide finance, design, construction, operation and maintenance of the state-of-the-art Botswana Children’s Hematology and Cancer Center which will be built next to the teaching hospital at the University of Botswana,” said Shenaaz el Halabi, permanent secretary at the Ministry of Health. “The Ministry of Health has had good relations with BIPAI dating as far back as 1999, which gave birth to the Baylor Children’s Center of Excellence in 2003. Since 2006, pediatric oncologists from Texas Children’s have been working at Princess Marina Hospital.”

The partnership responsible for the development and management of the Children’s Cancer Center includes: the Botswana Ministry of Health, Baylor College of Medicine Pediatric AIDS Initiative (BIPAI) and Texas Children’s.

May 3, 2016

42716cornynzika640On April 22, Sen. John Cornyn of Texas listened to Texas Medical Center doctors and Houston city officials break down research efforts on the Zika virus as mosquito season gets underway. The roundtable discussion was held at Texas Children’s Hospital and included a tour of the lab where research is being done and where Texas Children’s and Houston Methodist Hospital developed the nation’s first hospital-based rapid test for the Zika virus.

The virus, which has spread rapidly through Central and South America in the last year, is transmitted between humans primarily through mosquito bites. People may not realize they’ve been infected with Zika virus because the majority of people will develop an asymptomatic or mild flu-like infection. However, the virus has heightened concern among pregnant women since it may increase the risk of microcephaly, a rare neurological birth defect in which babies are born with abnormally small heads.

While there is no vaccine to protect against Zika infection, doctors are encouraging people, particularly pregnant women, to refrain from traveling to areas where the outbreak is growing. The only way to prevent infection is to avoid getting mosquito bites.

Cornyn said what he learned from the roundtable discussion was that the risk of under reacting to the Zika virus is too high and that the virus will be a problem in the United States if it is not stopped in Central and South America. As a result, he said he will recommend to Congress that action continue to be taken and that dollars continue to be allocated to taking a look at what needs to be done to stop what he called a devastating virus.

“We need to make sure we remain vigilant,” Cornyn said. “And, thanks to the great scientists and medical professionals we have here in Houston, Texas and around the country, I’m confident we will be at the cutting edge of new discoveries that will help public health across the globe.”

Click here to read excerpts from the roundtable discussion and here for more information on the Zika virus.

April 12, 2016

41316malaria640The Baylor College of Medicine International Pediatric AIDS Initiative (BIPAI) and Texas Children’s Global Health have been helping meet the health care needs of mothers and babies across the globe for years. With global health programs and projects in more than 20 countries, BIPAI and Texas Children’s Global Health have developed a network of partners who are sometimes called on to respond to emergency situations. For these scenarios, we often turn to Medical Bridges, a Houston-based non-profit that provides medical supplies and equipment to support our work.

Recently, BIPAI and Texas Children’s Global Health addressed pediatric emergencies in Papua New Guinea and during the Ebola crisis, in Liberia, with the help of Medical Bridges. Presently, there is an outbreak of malaria among pediatric patients in Luanda, Angola.

To address this health emergency, BIPAI, Texas Children’s Global Health and Texas Children’s Pediatric Hematology & Oncology program have partnered with Medical Bridges, Chevron and SonAir, an Angolan national air services company, to provide drugs, supplies and equipment to the Hospital Pediatrico David Bernardino (Bernadino Pediatric Hospital) in Luanda and to the hospital in Cacuaco. These much-needed drugs and supplies will help the staff at the hospitals address the recent outbreak of malaria among the pediatric population.

“BIPAI and Texas Children’s Global Health are fortunate to have partners like Chevron and Medical Bridges that can mobilize and respond proactively to public health emergencies around the world,” said Michael Mizwa, leader of BIPAI and Texas Children’s Global Health.

Ali Moshiri, president of Chevron Africa and Latin America Exploration and Production Company, said the company is proud to be able to help mitigate public health situations such as these.

“We value our partnership with BIPAI and Texas Children’s Global Health,” Moshiri said. “This contribution underscores Chevron’s long-standing commitment to fight malaria and to the children of Angola who are most at risk for the disease”

The Baylor College of Medicine International Pediatric AIDS Initiative (BIPAI) and Texas Children’s Global Pediatric Hematology & Oncology program started an Angola Sickle Cell Initiative (ASCI) in 2011 with generous support from Chevron, aimed at bringing neonatal Sickle Cell Disease (SCD) screening and care to two regions in Angola: Luanda and Cabinda. To date, 135,000 babies have been screened and, in 2015, with a donation from Bristol-Myers Squibb (BMS), the first organized Hydroxyurea (HU) treatment program for Angola was begun.

April 8, 2016

4716Malawi550

The United States Agency for International Development (USAID) has awarded a $69.8 million grant to the Baylor College of Medicine Children’s Foundation–Malawi (Baylor–Malawi), an affiliate of the Baylor College of Medicine International Pediatrics AIDS Initiative at Texas Children’s Hospital, to support and expand HIV/AIDS programs in Southern Africa. The grant, through the USAID Regional HIV-AIDS Program, will fund a dynamic and innovative project called Technical Support to PEPFAR Programs in the Southern Africa Region, or TSP. Designed by the Baylor-Malawi team, TSP is a collaborative program that includes ICAP at Columbia University and Baylor College of Medicine Children’s Foundations in Botswana, Swaziland, Lesotho and Angola.

“While Southern Africa remains the epicenter of the HIV/AIDS epidemic, recent progress toward global elimination goals provides an impetus for coordinated, regional efforts,” said Dr. Saeed Ahmed, assistant professor of pediatrics with BIPAI who will lead TSP. “The program will address challenges related to HIV care and treatment, including pediatric and adolescent care, HIV prevention from mother to child and the unique gender aspects of the epidemic, providing a common regional platform for dissemination and rapid adoption of best practices.”

In support of the primary goal to reduce the impact of HIV/AIDS in Southern Africa, TSP objectives are to:
Improve clinical and other technical outcomes of partner programs in the region by providing mission programs with technical support and short- and medium-term program assistance and capacity building toward sustainability;

Improve and rapidly expand pediatric and adolescent treatment services in the region by providing technical assistance in the short and medium term and longterm program support;

Implement PEPFAR programs directly, in close cooperation with USAID.

The TSP will provide a wealth of technical expertise, Ahmed said, including human resource capacity, physical infrastructure, existing networking and program implementation experience, bringing together formally the unique and complementary strengths of the Baylor network and ICAP at Columbia University. The Baylor foundations are the leading providers of pediatric and adolescent HIV care and treatment in their respective countries with Centers of Excellence anchoring broad networks of satellite clinics. ICAP, the second-largest PEPFAR implementing program, offers incredible geographic scope and technical, programmatic and monitoring and evaluation expertise. Combined, the Baylor network and ICAP have managed more than $1 billion in funding over the past 5 years, and are implementing more than 50 U.S. Government supported initiatives.

To provide assistance to regional HIV/AIDS programs, Baylor-Malawi and its partners have organized a ‘Dream Team’ of experts who will provide the technical advising backbone of the program. Through its implementing partners, the Dream Team will have access to an extensive network of more than 1,500 people, including doctors, nurses, social workers, counselors, community health workers and volunteers, and pharmacists to provideHIV/AIDS program assistance and implementation.

“The high-quality assistance and program implementation provided by this project will strengthen the efforts in the region to achieve the UNAIDS 90-90-90 benchmarks, which call for 90 percent of HIV-infected individuals to know their status; 90 percent of patients who know their status to be started on and adherent to anti-retroviral therapy; and 90 percent of patients on ART to be viral suppressed by 2020” said Dr. Mark Kline, physician-in-chief, Texas Children’s Hospital and chairman of the department of pediatrics, Baylor College of Medicine.

Women and children are a special focus on the TSP program. It aims to achieve elimination of mother-to-child transmission, doubling of the number of children on anti-retroviral therapy and, through the DREAMS Initiative, assisting partners in developing interventions to address gender-based violence and reduce new HIV infections in adolescent girls and young women. DREAMS, or Determined, Resilient, AIDS-free, Mentored and Safe Women, is a PEPFAR program to reduce HIV infections among girls and young women in sub-Saharan Africa.

“This award is a true testament to the BIPAI Network’s ability and capacity as a global leader in pediatric HIV/AIDS and tuberculosis. Baylor–Malawi continues to excel in innovative program development,” said Michael Mizwa, chairman, Baylor–Malawi Board of Directors, chief operating office/senior vice president of BIPAI and director of global health at Texas Children’s Hospital.

“With the resources from this award, I am pleased that Baylor Malawi will lead a consortium that leverages the extensive expertise that is in the BIPAI network with its partners ICAP and regional ministries of health to accelerate the region’s advances to the 90-90-90 targets,” said Dr. Peter Kazembe, executive director of Baylor College of Medicine Children’s Foundation–Malawi.

September 1, 2015

bench-and-beside-Header2Bench and Bedside is a digest of the previous month’s stories about the clinical and academic activities of our physicians and scientists. We welcome your submissions and feedback.

August 4

Department of Urology to present 12 papers at international conference

The Department of Urology will be well represented at the 26th Congress of the European Society for Paediatric Urology this October in Prague. Twelve of the department’s abstracts were chosen for posters, most with presentations.

August 4

Zoghbi receives seven-year Javits award to advance ataxia research

Dr. Huda Zoghbi, a Howard Hughes Medical Institute investigator and the director of the Jan and Dan Duncan Neurological Research Institute (NRI) at Texas Children’s, has been awarded a Javits Neuroscience Investigator Award from the National Institute of Neurological Disorders and Stroke for her “distinguished record of substantial contributions in the field of neurological science.”

9115tcpanniv300August 4

Texas Children’s Pediatrics celebrates 20 years of providing primary care

Twenty years ago today, Texas Children’s launched what is now the largest pediatric network in the nation with more than 200 board-certified pediatricians and 50 practices throughout the greater Houston community. Each year, the group sees 400,000 patients and completes more than a million visits.

9115chagas300August 4

Grant funds first therapeutic vaccine for Chagas disease in humans

The Sabin Vaccine Institute and Texas Children’s Hospital Center for Vaccine Development have received a $1.8 million grant to accelerate development of the first therapeutic vaccine for Chagas disease in humans. The vaccine is in a development program under the direction of Drs. Peter Hotez and Maria Elena Bottazzi. Chagas disease impacts people throughout Texas, and Texas Children’s is leading the way in vaccine development.

9115woodlandsurgentcare300August 18

Texas Children’s opens urgent care center in The Woodlands

Texas Children’s has expanded its urgent care network, adding a location in The Woodlands next door to the community’s children’s museum on West Panther Creek Drive.

 

 

August 18

Texas Children’s Hospital is a sponsor for the 2015 Be The Match Walk-Run

Be The Match Walk-Run is a fundraising event that helps patients find a bone marrow, stem cell, or cord donor and receive a life-saving transplant. Each year the Texas Children’s Bone Marrow Transplant Program has a group of patients, employees and their families who walk or run in support of this life saving research. You and your family are invited to join us as we support and raise awareness for the Be The Match registry.

9115autismwalk300August 18

Join the NRI, Baylor team for the 2015 Walk Now for Autism Speaks

Ready to lace up to support a worthy cause? The Jan and Dan Duncan Neurological Research Institute at Texas Children’s and Baylor College of Medicine invite you to join their team for the 2015 Walk Now for Autism Speaks.